Case Report Open Access

Presumed tubercular unilateral occlusive vasculitis mimicking frosted branch angiitis with bilateral serpiginous-like choroiditis: A challenging asymptomatic case

Evelien Janssen, Veerle Van Severen, Vincent M. De La Porte

Purpose: To present a challenging case of tubercular uveitis in an asymptomatic patient, featuring unilateral occlusive vasculitis with a frosted branch angiitis phenotype and bilateral serpiginous-like choroiditis.
Methods: Case report with clinical photography.

Mini Review Open Access

High resolution ultrasound and surveillance of the augmented breast

Caroline Glicksman, Sarah Ferenz, Marshall Kadin, Patricia McGuire

Approximately 35 million women worldwide have silicone breast implants. Like all medical devices, breast implants are not lifelong, and all will eventually need to be removed, with or without replacement. In 2019, the U.S. Food and Drug Administration (FDA) updated its guidance on breast implant surveillance to include HRUS screening for silent rupture. 

Systematic Review Open Access

Autoimmune hepatic involvement in systemic sclerosis—systematic review and meta-analysis

Gurleen Kaur, Palak Grover, Bipneet Singh, Rahul Jain, Karanbir Singh, Merritt Bern

Systemic sclerosis (SSc) is a heterogeneous, multisystem autoimmune disease characterized by fibrosis in genetically predisposed individuals. It can involve multiple organ systems, but hepatic involvement is rare. 

Commentary Open Access

Pancreatic cancer therapy in the era of precision oncology

Sakarie Mustafe Hidig

Pancreatic cancer, predominantly pancreatic ductal adenocarcinoma (PDAC), remains one of the most lethal malignancies, characterized by late diagnosis, aggressive tumor biology, and profound resistance to conventional therapies. Despite advances in surgical techniques and combination chemotherapy regimens such as FOLFIRINOX and gemcitabine-based therapies, survival outcomes remain poor, with five-year survival rates barely exceeding 10%. 

Case Report Open Access

Prehospital anesthesia-led resuscitation during traumatic cardiac arrest following prolonged extrication: a case report

Alexis Martinez, Michael Broussard, Mary Scott-Herring

Background: Traumatic cardiac arrest during prolonged extrication presents significant physiologic challenges. While prehospital care traditionally relies on emergency medical services personnel, select systems deploy hospital-based teams capable of delivering advanced anesthetic and resuscitative interventions at the scene. 

Commentary Open Access

Glimpsing the richness of intercellular dialogue in a snail embryo

Morgan Q Goulding

Snail embryos are textbook exemplars of autonomous cellular decision-making: in their spiral cleavage nearly every early cell division is asymmetric and oriented, creating a stereotyped and elaborate early pattern of fate-restricted cells (Figure 1A) reminiscent of the preformationist ‘homunculus’ fantasy.